Human MESD activation kit by CRISPRa

CAT#: GA108104

MESD CRISPRa kit - CRISPR gene activation of human mesoderm development LRP chaperone



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CNY 12255.00


货期*
4周

规格
    • 1 kit

Product images

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol MESD
Locus ID 23184
Kit Components

GA108104G1, MESD gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108104G2, MESD gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108104G3, MESD gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Reference Data
RefSeq NM_015154, NR_126327, NR_126328
Synonyms BOCA; MESD
Summary Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction. Plays an essential role in neuromuscular junction (NMJ) formation by promoting cell-surface expression of LRP4 (By similarity). May regulate phagocytosis of apoptotic retinal pigment epithelium (RPE) cells (By similarity).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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