Human Sulfatase 1 (SULF1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SULF1
Locus ID	23213
Kit Components	GA108130G1, Sulfatase 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108130G2, Sulfatase 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108130G3, Sulfatase 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001128204, NM_001128205, NM_001128206, NM_015170, NR_132437, NR_156415, NR_156414
Synonyms	HSULF-1; SULF-1
Summary	This gene encodes an extracellular heparan sulfate endosulfatase. The encoded enzyme selectively removes 6-O-sulfate groups from heparan sulfate chains of heparan sulfate proteoglycans (HSPGs). The enzyme is secreted through the Golgi and is subsequently localized to the cell surface. The expression of this gene may be down-regulated in several types of cancer, including hepatocellular (HCC), ovarian and breast cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

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