Human ARHGEF9 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ARHGEF9
Locus ID	23229
Kit Components	GA108143G1, ARHGEF9 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108143G2, ARHGEF9 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108143G3, ARHGEF9 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001173479, NM_001173480, NM_001330495, NM_015185, NM_001353921, NM_001353922, NM_001353923, NM_001353924, NM_001353926, NM_001353927, NM_001353928, NM_001369031, NM_001369036, NM_001369037, NM_001369039, NM_001369041, NM_001369043, NM_001369044, NM_001369045, NM_001369030, NM_001369032, NM_001369033, NM_001369034, NM_001369035, NM_001369038, NM_001369040, NM_001369042
Synonyms	COLLYBISTIN; EIEE8; HPEM-2; PEM-2; PEM2
Summary	The protein encoded by this gene is a Rho-like GTPase that switches between the active (GTP-bound) state and inactive (GDP-bound) state to regulate CDC42 and other genes. This brain-specific protein also acts as an adaptor protein for the recruitment of gephyrin and together these proteins facilitate receceptor recruitement in GABAnergic and glycinergic synapses. Defects in this gene are the cause of startle disease with epilepsy (STHEE), also known as hyperekplexia with epilepsy, as well as several other types of cognitive disability. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2017]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.