Human ARHGEF14 (MCF2L) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MCF2L
Locus ID	23263
Kit Components	GA108173G1, ARHGEF14 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108173G2, ARHGEF14 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108173G3, ARHGEF14 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001112732, NM_001320815, NM_001320816, NM_001320817, NM_024979, NM_001366644, NM_001366645, NM_001366646
Synonyms	ARHGEF14; DBS; OST
Summary	This gene encodes a guanine nucleotide exchange factor that interacts specifically with the GTP-bound Rac1 and plays a role in the Rho/Rac signaling pathways. A variant in this gene was associated with osteoarthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

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