Human POFUT2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	POFUT2
Locus ID	23275
Kit Components	GA108183G1, POFUT2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108183G2, POFUT2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108183G3, POFUT2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_015227, NM_133634, NM_133635, NR_004858, NR_148026
Synonyms	C21orf80; FUT13
Summary	Fucose is typically found as a terminal modification of branched chain glycoconjugates, but it also exists in direct O-linkage to serine or threonine residues within cystine knot motifs in epidermal growth factor (EGF; MIM 131530)-like repeats or thrombospondin (THBS; see MIM 188060) type-1 repeats. POFUT2 is an O-fucosyltransferase that use THBS type-1 repeats as substrates (Luo et al., 2006 [PubMed 16464857]).[supplied by OMIM, Mar 2008]

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