Human Nesprin 1 (SYNE1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SYNE1
Locus ID	23345
Kit Components	GA108235G1, Nesprin 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108235G2, Nesprin 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108235G3, Nesprin 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_015293, NM_033071, NM_133650, NM_182961, NM_001347701, NM_001347702
Synonyms	8B; ARCA1; C6orf98; CPG2; dJ45H2.2; DKFZp781J13156; EDMD4; FLJ30878; FLJ41140; KIAA0796
Summary	This gene encodes a spectrin repeat containing protein expressed in skeletal and smooth muscle, and peripheral blood lymphocytes, that localizes to the nuclear membrane. Mutations in this gene have been associated with autosomal recessive spinocerebellar ataxia 8, also referred to as autosomal recessive cerebellar ataxia type 1 or recessive ataxia of Beauce. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

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