Human COMMD3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	COMMD3
Locus ID	23412
Kit Components	GA108290G1, COMMD3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108290G2, COMMD3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108290G3, COMMD3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_012071
Synonyms	BUP; C10orf8
Summary	May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). May down-regulate activation of NF-kappa-B (PubMed:15799966). Modulates Na(+) transport in epithelial cells by regulation of apical cell surface expression of amiloride-sensitive sodium channel (ENaC) subunits (PubMed:23637203).[UniProtKB/Swiss-Prot Function]

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