Human ETHE1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ETHE1
Locus ID	23474
Kit Components	GA108331G1, ETHE1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108331G2, ETHE1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108331G3, ETHE1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001320867, NM_001320868, NM_001320869, NM_014297
Synonyms	HSCO; YF13H12
Summary	This gene encodes a member of the metallo beta-lactamase family of iron-containing proteins involved in the mitochondrial sulfide oxidation pathway. The encoded protein catalyzes the oxidation of a persulfide substrate to sulfite. Certain mutations in this gene cause ethylmalonic encephalopathy, an infantile metabolic disorder affecting the brain, gastrointestinal tract and peripheral vessels. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]

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