Human BRD4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	BRD4
Locus ID	23476
Kit Components	GA108333G1, BRD4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108333G2, BRD4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108333G3, BRD4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001330384, NM_014299, NM_058243
Synonyms	CAP; HUNK1; HUNKI; MCAP
Summary	The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]

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