Human SCRIBBLE (SCRIB) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SCRIB
Locus ID	23513
Kit Components	GA108357G1, SCRIBBLE gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108357G2, SCRIBBLE gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108357G3, SCRIBBLE gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_015356, NM_182706
Synonyms	CRIB1; SCRB1; SCRIB1; Vartul
Summary	This gene encodes a protein that was identified as being similar to the Drosophila scribble protein. The mammalian protein is involved in tumor suppression pathways. As a scaffold protein involved in cell polarization processes, this protein binds to many other proteins. The encoded protein binds to papillomavirus E6 protein via its PDZ domain and the C-terminus of E6. Two alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

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