Human C17orf81 (ELP5) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ELP5
Locus ID	23587
Kit Components	GA108416G1, C17orf81 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108416G2, C17orf81 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108416G3, C17orf81 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_015362, NM_203413, NM_203414, NM_203415, NR_145515
Synonyms	C17orf81; DERP6; HSPC002; MST071; MSTP071
Summary	Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. Involved in cell migration (By similarity). May be involved in TP53-mediated transcriptional regulation.[UniProtKB/Swiss-Prot Function]

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