Human LDOC1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	LDOC1
Locus ID	23641
Kit Components	GA108454G1, LDOC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108454G2, LDOC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108454G3, LDOC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_012317
Synonyms	BCUR1; Mar7; Mart7
Summary	The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. [provided by RefSeq, Jul 2008]

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