Human PGEA1 (CBY1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CBY1
Locus ID	25776
Kit Components	GA108529G1, PGEA1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108529G2, PGEA1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108529G3, PGEA1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001002880, NM_015373
Synonyms	arb1; C22orf2; CBY; HS508I15A; PGEA1; PIGEA-14; PIGEA14
Summary	Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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