Human TNFAIP8 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TNFAIP8
Locus ID	25816
Kit Components	GA108556G1, TNFAIP8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108556G2, TNFAIP8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108556G3, TNFAIP8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001077654, NM_001286813, NM_001286814, NM_001286815, NM_001286817, NM_014350
Synonyms	GG2-1; MDC-3.13; NDED; SCC-S2; SCCS2
Summary	Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.[UniProtKB/Swiss-Prot Function]

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