Human DNAJB5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DNAJB5
Locus ID	25822
Kit Components	GA108562G1, DNAJB5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108562G2, DNAJB5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108562G3, DNAJB5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001135004, NM_001135005, NM_012266, NM_001349723, NM_001349724, NM_001349725
Synonyms	Hsc40
Summary	This gene encodes a member of the DNAJ heat shock protein 40 family of co-chaperone proteins. The encoded protein contains an N-terminal DNAJ domain and a C-terminal substrate binding domain but lacks the cysteine-rich domain found in other DNAJ family members. In mice, a multi-protein complex containing this protein, thioredoxin 1, and histone deacetylase 4, serves as a master negative regulator of cardiac hypertrophy. [provided by RefSeq, Mar 2017]

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