Human SUMF2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SUMF2
Locus ID	25870
Kit Components	GA108595G1, SUMF2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108595G2, SUMF2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108595G3, SUMF2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001042468, NM_001042469, NM_001042470, NM_001130069, NM_001130070, NM_001146333, NM_015411, NM_001366647, NM_001366648, NM_001366649
Synonyms	DKFZp566I1024; DKFZp686I1024; DKFZp686L17160; DKFZp781L1035; MGC99485; pFGE
Summary	The catalytic sites of sulfatases are only active if they contain a unique amino acid, C-alpha-formylglycine (FGly). The FGly residue is posttranslationally generated from a cysteine by enzymes with FGly-generating activity. The gene described in this record is a member of the sulfatase-modifying factor family and encodes a protein with a DUF323 domain that localizes to the lumen of the endoplasmic reticulum. This protein has low levels of FGly-generating activity but can heterodimerize with another family member - a protein with high levels of FGly-generating activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

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