Human TRIM58 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TRIM58
Locus ID	25893
Kit Components	GA108610G1, TRIM58 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108610G2, TRIM58 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108610G3, TRIM58 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_015431
Synonyms	BIA2
Summary	E3 ubiquitin ligase induced during late erythropoiesis. Directly binds and ubiquitinates the intermediate chain of the microtubule motor dynein (DYNC1LI1/DYNC1LI2), stimulating the degradation of the dynein holoprotein complex. May participate in the erythroblast enucleation process through regulation of nuclear polarization.[UniProtKB/Swiss-Prot Function]

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