Human CHORDC1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CHORDC1
Locus ID	26973
Kit Components	GA108950G1, CHORDC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108950G2, CHORDC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108950G3, CHORDC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001144073, NM_012124
Synonyms	CHP1
Summary	Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Proposed to act as co-chaperone for HSP90. May play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, has intrinsic chaperone activity. This function may be achieved by inhibiting association of ROCK2 with NPM1. Involved in stress response. Prevents tumorigenesis.[UniProtKB/Swiss-Prot Function]

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