Human DISC1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DISC1
Locus ID	27185
Kit Components	GA109058G1, DISC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109058G2, DISC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109058G3, DISC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001012957, NM_001012958, NM_001012959, NM_001164537, NM_001164538, NM_001164539, NM_001164540, NM_001164541, NM_001164542, NM_001164544, NM_001164545, NM_001164546, NM_001164547, NM_001164548, NM_001164549, NM_001164550, NM_001164551, NM_001164552, NM_001164553, NM_001164554, NM_001164555, NM_001164556, NM_018662
Synonyms	C1orf136; SCZD9
Summary	This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

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