Human C5L2 (C5AR2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	C5AR2
Locus ID	27202
Kit Components	GA109065G1, C5L2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109065G2, C5L2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109065G3, C5L2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001271749, NM_001271750, NM_018485
Synonyms	C5L2; GPF77; GPR77
Summary	This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]

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