Human ITGB1BP3 (NMRK2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NMRK2
Locus ID	27231
Kit Components	GA109068G1, ITGB1BP3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109068G2, ITGB1BP3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109068G3, ITGB1BP3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001289117, NM_014446, NM_170678, NR_110316
Synonyms	ITGB1BP3; MIBP; NRK2
Summary	Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). Reduces laminin matrix deposition and cell adhesion to laminin, but not to fibronectin. Involved in the regulation of PXN at the protein level and of PXN tyrosine phosphorylation. May play a role in the regulation of terminal myogenesis.[UniProtKB/Swiss-Prot Function]

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