Human UBN1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	UBN1
Locus ID	29855
Kit Components	GA109284G1, UBN1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109284G2, UBN1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109284G3, UBN1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001079514, NM_001288656, NM_016936
Synonyms	VT; VT4
Summary	Cellular senescence is a hallmark of tumor suppression and tissue aging. Senescent cells contain domains of heterochromatin, called senescence-associated heterochromatin foci (SAHF), that repress proliferation-promoting genes. The protein encoded by this gene binds to proliferation-promoting genes and is required for SAHF formation, enhancing methylation of histone H3. [provided by RefSeq, Oct 2016]

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