Human GNL2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GNL2
Locus ID	29889
Kit Components	GA109292G1, GNL2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109292G2, GNL2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109292G3, GNL2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001323623, NM_001323624, NM_013285
Synonyms	HUMAUANTIG; Ngp-1; NGP1; Nog2; Nug2
Summary	GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (By similarity). May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels (PubMed:26203195).[UniProtKB/Swiss-Prot Function]

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