Human DUOX2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DUOX2
Locus ID	50506
Kit Components	GA109419G1, DUOX2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109419G2, DUOX2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109419G3, DUOX2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_014080, NM_001363711
Synonyms	LNOX2; NOXEF2; P138-TOX; TDH6; THOX2
Summary	The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX1. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. [provided by RefSeq, Jul 2008]

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