Human ThPok (ZBTB7B) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ZBTB7B
Locus ID	51043
Kit Components	GA109518G1, ThPok gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109518G2, ThPok gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109518G3, ThPok gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001252406, NM_001256455, NM_015872, NR_045515, NR_046206, NR_049765
Synonyms	c-KROX; CKROX; hcKROX; THPOK; ZBTB15; ZFP-67; ZFP67; ZNF857B
Summary	This gene encodes a zinc finger-containing transcription factor that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. It also functions as a transcriptional repressor of type I collagen genes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]

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