Human RNF12 (RLIM) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RLIM
Locus ID	51132
Kit Components	GA109594G1, RNF12 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109594G2, RNF12 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109594G3, RNF12 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_016120, NM_183353
Synonyms	NY-REN-43; RNF12
Summary	The protein encoded by this gene is a RING-H2 zinc finger protein. It has been shown to be an E3 ubiquitin protein ligase that targets LIM domain binding 1 (LDB1/CLIM), and causes proteasome-dependent degradation of LDB1. This protein and LDB1 are co-repressors of LHX1/LIM-1, a homeodomain transcription factor. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Feb 2009]

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