Human C5orf45 (MRNIP) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MRNIP
Locus ID	51149
Kit Components	GA109607G1, C5orf45 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109607G2, C5orf45 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109607G3, C5orf45 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001017987, NM_001018061, NM_001018062, NM_016175
Synonyms	DKFZp686L2452; MGC65027; MGC78537
Summary	Plays a role in the cellular response to DNA damage and the maintenance of genome stability through its association with the MRN damage-sensing complex (PubMed:27568553). Promotes chromatin loading and activity of the MRN complex to facilitate subsequent ATM-mediated DNA damage response signaling and DNA repair (PubMed:27568553).[UniProtKB/Swiss-Prot Function]

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