Human EDD (UBR5) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	UBR5
Locus ID	51366
Kit Components	GA109767G1, EDD gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109767G2, EDD gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109767G3, EDD gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001282873, NM_015902
Synonyms	DD5; EDD; EDD1; HYD
Summary	This gene encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation. [provided by RefSeq, Jul 2008]

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