Human MRPS17 activation kit by CRISPRa

CAT#: GA109772

MRPS17 CRISPRa kit - CRISPR gene activation of human mitochondrial ribosomal protein S17



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CNY 12255.00


货期*
4周

规格
    • 1 kit

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MRPS17 (Myc-DDK-tagged)-Human mitochondrial ribosomal protein S17 (MRPS17), nuclear gene encoding mitochondrial protein
    • 10 ug

CNY 1800.00
CNY 3705.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol MRPS17
Locus ID 51373
Kit Components

GA109772G1, MRPS17 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA109772G2, MRPS17 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA109772G3, MRPS17 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Reference Data
RefSeq NM_015969
Synonyms HSPC011; MRP-S17; RPMS17; S17mt
Summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S17P family. The encoded protein is moderately conserved between human mitochondrial and prokaryotic ribosomal proteins. Pseudogenes corresponding to this gene are found on chromosomes 1p, 3p, 6q, 14p, 18q, and Xq. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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