Human UCH37 (UCHL5) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	UCHL5
Locus ID	51377
Kit Components	GA109775G1, UCH37 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109775G2, UCH37 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109775G3, UCH37 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001199261, NM_001199262, NM_001199263, NM_015984, NR_037607, NM_001350840, NM_001350841, NM_001350842, NM_001350843, NM_001350844, NM_001350845, NM_001350846, NM_001350847, NM_001350848, NM_001350849, NM_001350850, NM_001350851, NM_001350852, NR_146930, NR_146931
Synonyms	CGI-70; INO80R; UCH-L5; UCH37
Summary	Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. Putative regulatory component of the INO80 complex; however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1.[UniProtKB/Swiss-Prot Function]

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