Human BIN2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	BIN2
Locus ID	51411
Kit Components	GA109793G1, BIN2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109793G2, BIN2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109793G3, BIN2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001290007, NM_001290008, NM_001290009, NM_016187, NM_016293, NM_001364780, NM_001364781, NM_001364779
Synonyms	BRAP-1
Summary	Promotes cell motility and migration, probably via its interaction with the cell membrane and with podosome proteins that mediate interaction with the cytoskeleton. Modulates membrane curvature and mediates membrane tubulation. Plays a role in podosome formation. Inhibits phagocytosis.[UniProtKB/Swiss-Prot Function]

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