Human RAP80 (UIMC1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	UIMC1
Locus ID	51720
Kit Components	GA109959G1, RAP80 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109959G2, RAP80 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109959G3, RAP80 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001199297, NM_001199298, NM_001317961, NM_016290, NR_146149, NR_146150
Synonyms	RAP80; X2HRIP110
Summary	This gene encodes a nuclear protein that interacts with Brca1 (breast cancer 1) in a complex to recognize and repair DNA lesions. This protein binds ubiquitinated lysine 63 of histone H2A and H2AX. This protein may also function as a repressor of transcription. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

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