Human BRCAA1 (ARID4B) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ARID4B
Locus ID	51742
Kit Components	GA109970G1, BRCAA1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109970G2, BRCAA1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109970G3, BRCAA1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001206794, NM_016374, NM_031371, NR_135074
Synonyms	BCAA; BRCAA1; RBBP1L1; RBP1L1; SAP180
Summary	This gene encodes a protein with sequence similarity to retinoblastoma-binding protein-1. The encoded protein is a subunit of the histone deacetylase-dependant SIN3A transcriptional corepressor complex, which functions in diverse cellular processes including proliferation, differentiation, apoptosis, oncogenesis, and cell fate determination. The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008]

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