Human EDG8 (S1PR5) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	S1PR5
Locus ID	53637
Kit Components	GA110021G1, EDG8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110021G2, EDG8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110021G3, EDG8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001166215, NM_030760
Synonyms	Edg-8; EDG8; S1P5; SPPR-1; SPPR-2
Summary	The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1; MIM 601974) are S1P receptors; others (e.g., EDG2; MIM 602282) are LPA receptors.[supplied by OMIM, Mar 2008]

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