Human EHM2 (EPB41L4B) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	EPB41L4B
Locus ID	54566
Kit Components	GA110182G1, EHM2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110182G2, EHM2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110182G3, EHM2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_018424, NM_019114
Synonyms	CG1; EHM2
Summary	Up-regulates the activity of the Rho guanine nucleotide exchange factor ARHGEF18 (By similarity). Involved in the regulation of the circumferential actomyosin belt in epithelial cells (PubMed:22006950). Promotes cellular adhesion, migration and motility in vitro and may play a role in wound healing (PubMed:23664528). May have a role in mediating cytoskeletal changes associated with steroid-induced cell differentiation (PubMed:14521927).[UniProtKB/Swiss-Prot Function]

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