Human FBXL19 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	FBXL19
Locus ID	54620
Kit Components	GA110200G1, FBXL19 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110200G2, FBXL19 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110200G3, FBXL19 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001099784, NM_001271651, NM_001282351, NM_019085, NR_073401
Synonyms	CXXC11; Fbl19; JHDM1C
Summary	This gene encodes a member of the Skp1-Cullin-F-box family of E3 ubiquitin ligases. The encoded protein is reported to bind to the transmembrane receptor interleukin 1 receptor-like 1 and regulate its ubiquitination and degradation. This protein has been linked to the regulation of pulmonary inflammation and psoriasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

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