Human SEMA4C activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SEMA4C
Locus ID	54910
Kit Components	GA110363G1, SEMA4C gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110363G2, SEMA4C gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110363G3, SEMA4C gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_017789
Synonyms	M-SEMA-F; SEMACL1; SEMAF; SEMAI
Summary	Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal brain development, axon guidance and cell migration (By similarity). Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade.[UniProtKB/Swiss-Prot Function]

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