Human UBC3B (UBE2R2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	UBE2R2
Locus ID	54926
Kit Components	GA110375G1, UBC3B gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110375G2, UBC3B gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110375G3, UBC3B gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_017811
Synonyms	CDC34B; E2-CDC34B; UBC3B
Summary	Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation. [provided by RefSeq, Jul 2008]

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