Human Gemin 8 (GEMIN8) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GEMIN8
Locus ID	54960
Kit Components	GA110406G1, Gemin 8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110406G2, Gemin 8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110406G3, Gemin 8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001042479, NM_001042480, NM_017856
Synonyms	FAM51A1
Summary	The protein encoded by this gene is part of the SMN complex, which is necessary for spliceosomal snRNP assembly in the cytoplasm and pre-mRNA splicing in the nucleus. The encoded protein binds to both SMN1 and the GEMIN6/GEMIN7 heterodimer, mediating their interaction. This protein is found in nuclear Gemini of Cajal bodies (gems) and in the cytoplasm. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010]

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