Human INT11 (CPSF3L) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	INTS11
Locus ID	54973
Kit Components	GA110418G1, INT11 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110418G2, INT11 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110418G3, INT11 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001256456, NM_001256460, NM_001256462, NM_001256463, NM_017871, NM_032179
Synonyms	CPSF73L; INT11; INTS11; RC-68; RC68
Summary	The Integrator complex contains at least 12 subunits and associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates the 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690). INTS11, or CPSF3L, is the catalytic subunit of the Integrator complex (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008]

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