Human PPP2R3C activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PPP2R3C
Locus ID	55012
Kit Components	GA110451G1, PPP2R3C gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110451G2, PPP2R3C gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110451G3, PPP2R3C gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001305155, NM_001305156, NM_017917, NR_130972
Synonyms	C14orf10; G4-1; G5pr
Summary	This gene encodes a regulatory subunit of the serine/threonine phosphatase, protein phosphatase 2. This protein is localized to both nuclear and cytoplasmic regions depending on cell cycle phase. Homozygous conditional knockout mice for this gene exhibit reduced numbers and impaired proliferation of immune system B cells. This protein may regulate the expression of the P-glycoprotein ATP-binding cassette transporter through its phosphatase activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]

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