Human XKR8 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	XKR8
Locus ID	55113
Kit Components	GA110525G1, XKR8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110525G2, XKR8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110525G3, XKR8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_018053
Synonyms	hXkr8; XRG8
Summary	Promotes phosphatidylserine exposure on apoptotic cell surface, possibly by mediating phospholipid scrambling. Phosphatidylserine is a specific marker only present at the surface of apoptotic cells and acts as a specific signal for engulfment. Has no effect on calcium-induced exposure of phosphatidylserine. Activated upon caspase cleavage, suggesting that it does not act prior the onset of apoptosis.[UniProtKB/Swiss-Prot Function]

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