Human RNF220 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RNF220
Locus ID	55182
Kit Components	GA110583G1, RNF220 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110583G2, RNF220 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110583G3, RNF220 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001319956, NM_001319957, NM_016501, NM_018150
Synonyms	C1orf164
Summary	E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B (By similarity). Independently of its E3 ligase activity, acts as a CTNNB1 stabilizer through USP7-mediated deubiquitination of CTNNB1 promoting Wnt signaling (PubMed:25266658).[UniProtKB/Swiss-Prot Function]

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