Human PACC1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PACC1
Locus ID	55248
Kit Components	GA110641G1, PACC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110641G2, PACC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110641G3, PACC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001198862, NM_018252
Synonyms	C1orf75
Summary	Proton-activated chloride channel that mediates import of chloride ion in response to extracellular acidic pH (PubMed:31023925). Involved in acidosis-induced cell death by mediating chloride influx and subsequent cell swelling (PubMed:31023925).[UniProtKB/Swiss-Prot Function]

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