Human THNSL2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	THNSL2
Locus ID	55258
Kit Components	GA110651G1, THNSL2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110651G2, THNSL2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110651G3, THNSL2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001244676, NM_001244678, NM_018271
Synonyms	SOFAT; THS2; TSH2
Summary	This gene encodes a threonine synthase-like protein. A similar enzyme in mouse can catalyze the degradation of O-phospho-homoserine to a-ketobutyrate, phosphate, and ammonia. This protein also has phospho-lyase activity on both gamma and beta phosphorylated substrates. In mouse an alternatively spliced form of this protein has been shown to act as a cytokine and can induce the production of the inflammatory cytokine IL6 in osteoblasts. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]

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