Human CDCA7L activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CDCA7L
Locus ID	55536
Kit Components	GA110782G1, CDCA7L gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110782G2, CDCA7L gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110782G3, CDCA7L gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001127370, NM_001127371, NM_018719
Synonyms	JPO2; R1; RAM2
Summary	Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.[UniProtKB/Swiss-Prot Function]

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