Human FAM48A (SUPT20H) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SUPT20H
Locus ID	55578
Kit Components	GA110800G1, FAM48A gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110800G2, FAM48A gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110800G3, FAM48A gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001014286, NM_001278480, NM_001278481, NM_001278482, NM_017569
Synonyms	C13; C13orf19; FAM48A; FP757; P38IP; SPT20
Summary	Required for MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) activation during gastrulation. Required for down-regulation of E-cadherin during gastrulation by regulating E-cadherin protein level downstream from NCK-interacting kinase (NIK) and independently of the regulation of transcription by FGF signaling and Snail (By similarity). Required for starvation-induced ATG9A trafficking during autophagy.[UniProtKB/Swiss-Prot Function]

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