Human C12orf11 (ASUN) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	INTS13
Locus ID	55726
Kit Components	GA110915G1, C12orf11 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110915G2, C12orf11 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110915G3, C12orf11 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_018164
Synonyms	C12orf11; GCT1; Mat89Bb; NET48; SPATA30
Summary	Crucial regulator of the mitotic cell cycle and development. At prophase, required for dynein anchoring to the nuclear envelope important for proper centrosome-nucleus coupling. At G2/M phase, may be required for proper spindle formation and execution of cytokinesis. Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing (PubMed:23904267).[UniProtKB/Swiss-Prot Function]

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