Human FTSJD1 (CMTR2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CMTR2
Locus ID	55783
Kit Components	GA110965G1, FTSJD1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110965G2, FTSJD1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110965G3, FTSJD1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001099642, NM_001324374, NM_001324377, NM_001324378, NM_001324379, NM_018348
Synonyms	AFT; FTSJD1; HMTr2; MTr2
Summary	S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap2 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the second nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) (cap0) to produce m(7)GpppRmpNm (cap2). Recognizes a guanosine cap on RNA independently of its N(7) methylation status. Display cap2 methylation on both cap0 and cap1. Displays a preference for cap1 RNAs.[UniProtKB/Swiss-Prot Function]

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