Human NRIP (DCAF6) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DCAF6
Locus ID	55827
Kit Components	GA111001G1, NRIP gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111001G2, NRIP gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111001G3, NRIP gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001017977, NM_001198956, NM_001198957, NM_018442, NM_001349773, NM_001349774, NM_001349775, NM_001349776, NM_001349777, NM_001349778, NM_001349779, NM_001349780, NR_146228, NR_146229, NR_146230
Synonyms	1200006M05Rik; ARCAP; IQWD1; MSTP055; NRIP; PC326
Summary	The protein encoded by this gene is a ligand-dependent coactivator of nuclear receptors, including nuclear receptor subfamily 3 group C member 1 (NR3C1), glucocorticoid receptor (GR), and androgen receptor (AR). The encoded protein and DNA damage binding protein 2 (DDB2) may act as tumor promoters and tumor suppressors, respectively, by regulating the level of androgen receptor in prostate tissues. In addition, this protein can act with glucocorticoid receptor to promote human papillomavirus gene expression. [provided by RefSeq, Mar 2017]

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